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For patients with non-alcoholic fatty liver disease or non-alcoholic steatohepatitis, tirzepatide represents one of the most effective interventions currently available

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in the UK, hydroxocobalamin is standard, typically given as a loading dose (e.g., 1 mg on alternate days for about 2 weeks), then 1 mg every 3 months (or every 2 months if neurological involvement is present) The NHS and The Vegan Society recommend that individuals at risk of deficiency, particularly vegans and older adults, consider regular B12 supplementation

Combining these two, GLP-1 offers a dual-action approach